１９９０年～１９９９年 執筆論文
○９０年
19 H. Sumi, H. Hamada, K. Nakanishi and H. Hiratani;
Enhancement of the fibrinolytic activity in plasma by oral administration of
Nattokinase,
Acta Haematologica, 84, pp.139-143 (1990)
20 H. Hamada and S. Kawabe;
The selectivity in the biotransformation of testosterones with the cultured cells of
Marchantia polymorpha,
5th European Congress on Biotechnology, pp.120-123 (1900)
21 H. Hamada, A. R. Jacobson, H. J. Williams and A. I. Scott;
Deacetylation of vindoline by buffered cell suspension cultures of Catharanthus
roseus,
Biotechnology Letters, 12(12), pp.897-898 (1990)
○９１年
22 H. Hamada and K. Nakazawa;
Biotransformation of vinblastine to vincristine by cell suspension cultures of Catharanthus
roseus,
Biotechnology Letters, 12 (11), pp.805-806 (1991)
23 H. Hamada, T. Hoshino and K. Ohsato;
The production of capillen in shoot primordisa of Artemisia capillaries,
Plant Tissue Culture Letters, 8 (3), pp.190-192 (1991)
24 H. Hamada and S. Kawabe;
Biotransformation of 4-androstene-3, 17-dione by green cell suspension Marchantio
polymorpha :
Stereoselective reduction at carbon 17,
Life Sciences, 48, pp.613-615 (1991)
25 H. Hamada, H. Konishi, H. J. Williams and A. I. Scott;
Biotransformation of testosterone isomers by a green cell suspension culture of Marchantio
polymorpha,
Phytochemistry, 30 (7),
pp.2269-2270 (1991)
○９２年
26 H. Hamada, H. J. Williams, Y. Gao and A. I. Scott;
13C NMR studies of plant cell culture metabolism using stirred aerated media :
Metabolism of 1-13C-glucose in Catharanthus roseus cell suspensions,
Biopractice, 1, pp.56-57 (1992)
27 M. Essenberg, G. D. Davis, M. Pierce, H. Hamada and G. Davila-Huerta;
Biosynthesis of sesquiterpenoid phytoalexins in cotton foliar tissue,
Secondary-Metabolite Biosynthesis and Metabolism, pp.297-304 (1992)
28 H.Hamada and S. Nakata;
Biotransformation of glycyrrhizin by buffered cell suspension cultures
of Catharanthus roseus,
Plant Tissue Culture Letters,
9 (1), pp.32-33 (1992)
29 浜田博喜, 長嶋美喜, 竹西壮一郎, 河邊誠一郎;
“ヨウシュヤマゴボウ培養細胞による細胞外へのベタシアニン放出－カルシウムイオンによる影響”,
植物組織培養, 9 (2),
pp.126－127 (1992)
○９３年
30 H. Hamada, Y. Fuchikami, R. L. Jansing and L. S. Kaminsky;
Regioselective hydroxylation of warfarin by cell suspension cultures of Catharanthus
roseus,
Phytochemistry, 33 (3),
pp.599-600 (1993)
31 H. Hamada, K. Nakazawa, H. J. Williams and A. I. Scott;
A significant increase in vindoline content of leaves of Catharanthus roseus
is induced by UV light irradiation,
Pharm. Pharmacol. Lett., 2, pp.218-219 (1993)
32 H. Hamada, K. Nkazawa, M. Inoguchi, H. J. Williams and A. I. Scott;
High level production of serpentine by tumorous Catharanthus roseus,
Pharm. Pharmacol. Lett., 3, pp.49-50 (1993)
33 H. Hamada, S. Naka and H. Kurban;
Stereoselective reduction in the biotransformation of androstane derivatives by cell
suspension cultures of
Marchantia polymorpha,
Chem. Lett., pp.2111-2112 (1993)
34 H. Hamada;
The regio- and stereoselective reaction in biotransformation of foreign substrate by
plant cell suspension cultures,
Advances in Developmental Biology and Biotechnology of Higher Plants,
pp.432-438 (1993)
○９４年
35 H. Hamada, N. Nakajima, Y. Shisa, M. Funahashi and K. Nakamura;
Enantioselective reduction of ethyl 3-methyl-2-oxobutanoate by enzymatic system from
callus of Catharanthus
roseus,
Bioorganic & Medicinal Chemistry Letters, 4 (7), pp.907-910 (1994)
36 T. Hirata, S. Izumi, T. Kido, Y. Ikeda, H. Hamada and T. Kawamura;
Introduction of oxygenated functional groups into monoterpene hydrocarbons with the
plant cultured cells,
Phytochemistry, 37 (2), pp.401-403 (1994)
37 H. Hamada, Y. Fuchikami, Y. Ikematsu, T. Hirata, H. Williama and A. I. Scott;
Hydroxylation of piperitone by cell suspension cultures of Catharanthus roseus,
Phytochemistry, 37 (4), pp.1037-1038 (1994)
38 H. Hamada, M. Imura and T. Okano;
Biotransformation of 1,1,1-trifluoroheptan-2-one and octan-2-one
by the cell suspension culture of Nicotiana tabacum-Acceleration by fluorine
substitution,
J. Biotech., 32, pp.89-92 (1994)
○９５年
39 K. Nakamura, H. Miyoshi, Y. Sugiyama and H. Hamada;
Diastereo- and enantioselective reduction of ethyl 2-methyl-3-oxobutanoate by plant
cell suspension cultures,
Phytochemistry,40 (5), pp.1419-1420 (1995)
40 G. Davila-Huerta, H. Hamada, G. G. Davis, R. D. Stipanovic, C. M. Adams and M.
Essenberg;
Cadinane-type sesquiterpenes induced in gossypium cotyledons by bacterial
inoculation,
Phytochemistry,39 (3), pp.531-536 (1995)
41 浜田博喜; “植物培養細胞を利用した物質変換”, 化学と生物,
33 (1), pp.11-12 (1995)
42 浜田博喜; “植物培養細胞からの新しい薬の創製”, 酵素工学ニュース,
33, pp.13-16 (1995)
○９６年
43 H. Hamada and T. Furuya;
Recent advances in plant biotransformation,
Plant Tissue Culture and Biotechnology, 2 (1), pp.52-59 (1996)
44 H. Hamada, M. Shiromoto, T. Funahashi, T. Itoh and K. Nakamura;
Efficient synthesis of optically pure 1,1,1-trifluoro-2-alkanols through
lipase-Catalyzed acylation in organic media,
J. Org. Chem., 61 (7), pp.2332-2336 (1996)
45 N. Nakajima, K. Ishihara, M. Sugimoto, H. Sumi, K. Mikuni and H. Hamada;
Chemical modification of earthworm fibrinolytic enzyme
with human serum albumin fragments and characterization of the protease as a
therapeutic enzyme,
Biosci. Biotech. Biochem., 60 (2), pp.293-300 (1996)
46 H. Hamada, K. Sanada, S. Ikeda, T. Oda, H. J. Williams, G. Moyna and A. I. Scott;
Epimerization of taxol in human cancer cells,
Natural Product Letters, 8, pp.113-117 (1996)
47 T. Itoh, M. Shiromoto, H. Inoue, H. Hamada and K. Nakamura;
Simple preparation of optical pure bis(trifluorometyl)-alkanediols through
lipase-Catalyzed reaction,
Tetrahedron Letters, 37 (28), pp.5001-5002 (1996)
48 H. Hamada, K. Sanada, T. Furuya, S. Kawabe and M. Jaziri;
Biotransformation of paclitaxel by cell suspension cultures of Eucalyptus
perriniana,
Natural Product Letters, 9, pp.47-52 (1996)
49 M. Jaziri, A. Zhiri, Y-W Guo, J-P Dupont, K. Shimomura, H. Hamada, M. Vanhaelen and J.
Homes;
Taxus sp. Cell, tissue and organ cultures as alternative sources for taxoids
production : a literature survey,
Plant Cell Tissue and Organ Culture, 46, pp.59-75 (1996)
50 Z. Siding, H. Hamada, K. Sanada and Anthony T. Tu;
Raman and ir spectroscopic study of taxol and its analogue, 10-deacetylbaccatin Ⅲ,
Vibrational Spectroscopy in press, (1996)
○９７年
51 H. Hamada, H. Yasumune, Y. Fuchikami, T. Hirata, I. Sattler, H. Williams and A.I.
Scott;
Biotransformation of geraniol, nerol and(+)- and(-)- carvone by suspension cultured
cells of Catharanthus roseus,
Phytochemistry, 44 (4), pp.615-621 (1997)
52 J. Yamada, M. Morisaki, K. Iwai, H. Hamada, N. Sato and Y. Fujimoto;
24-Methyl-and 24-ethyl-24(25)-cholesterols as immediate biosynthetic precursors of
24-alkylsterols in higher
plants,
Tetrahedron, 53 (3), pp.877-884 (1997)
53 T. Furuya, Y. Asada, Y. Matsuura, S. Mizobata and H. Hamada;
Biotransformation of β-thujaplicin by cultured cells of Eucalyptus perriniana,
Phytochemistry, 46 (8), pp.1355-1358 (1997)
54 H. Hamada and T. Furuya;
The selectivity by plant biotransformation T.- J. Fu et al., Plant Cell and Tissue
Culture for the Production of Food
Ingredient,
Plenum Publishing Corporation, pp.113-120 (1999)
55 Y. Fujimoto, N. Sato, K. Iwai, H. Hamada, J. Yamada and M. Morisaki;
Stereochemistry of the reduction of 24-methyldemosterol to campestererol
dihydrobrassicasterol in higher plants,
Chem. Commun., pp.681-682 (1997)
56 N. Nakajima, T. Furuya, K. Ishihara, S. Matsumura, S. Mizobata and H. Hamada;
Enzymatic production of β-thujaplicin 2-O-β-glucoside
in a membrane reactor using an insoluble UDP-glucosyltransferase fraction from
cultured cells of Eucalyptus
perriniana,
Journal of Fermentation and Bioengineering, 84 (5), pp.455-460 (1997)
57 N. Nakajima, K. Ishihara, S. Matsumura, H. Hamada, K. Nakamura and T. Furuya;
Lipase-catalyzed synthesis of arbutin cinnamate in an organic solvent and
application of transesterification to
stabiliza plant pigments,
Biosci. Biotech. Biochem., 61 (11), pp.1926-1928 (1997)
58 T. Itoh, K. Mitsukura, K. Kaihatsu, H. Hamada, Y. Takagi and H. Tsukube;
Remarkable acceleration of a lipase-catalyzed reaction by a thiacrown ether
additive:
buffer-free highly regioselective partial hydrolysis of 4-acetoxy-2-metylbut- 2-enyl
acetate,
J. Chem. Soc., Perkin Trans, 1, pp.2275-2278 (1997)
○９８年
59 Y. Fujimoto, N. Sato, Y. Sekiyama, M. Ito, T. Suzuki, H. Hamada and M. Morisaki;
Metabolic organic of C-26 and C-27 of isofucosterol in tissue cultures of Catharanthus
roseus,
Natural Product Letters, (1998)
60 H. Hamada, Y. Miyamoto, N. Nakajima and T.
Furuya; Highly selective transformation by plant catalysts,
Journal of Molecular Catalysis B: Enzymatic(1998)
61 Y. Yamamoto, A. Hachiya, H. Hamada and H. Matsumoto;
Phenylpropanoids as a protectant of aluminum toxicity in cultured tobacco cells,
Plant cell Physiol., 39(9), pp.950-957 (1998)
62 T. Furuya, Y. Asada, S. Nizobata, Y. Matsuura and H. Hamada;
Biotransformation of p-aminobenzoic acid by cultured cells of Eucalyptus
perriniana,
Phytochemistry, 49 (1), pp.109-111 (1998)
63 H. J. Williams, G. Moyna, A. I. Scott, H. Hamada, W. W. Warlwin, T. Tanaka and T.
Furuya;
Biotransformation products of (5R)-(+)-pulegone and (2S,5R)-(-)-menthone produced by
cultured cells of
Catharanthus roseus,
J. Indian Chem., 75, pp.838-840 (1998)
○９９年
64 N. Nakajima, K. Ishihara, T. Itoh, T. Furuya and H. Hamada;
Lipase-catalyzed direct and regioselective acylation of flavonoid glucoside for
mechanistic investigation of stable
plant pigments,
Journal of Bioscience and Bioengineering, 87 (1), pp.105-107 (1999)
65 N. Nakajima, K. Ishihara, H. Hamada, S. Yamane, K. Nakamura and T. Furuya;
Multi-enzymatic glucosylation using Eucalyptus UDP-glucosyltransferase coupled
UDPglucose-fermentation by
baker's yeast,
Biosci. Biotechnol. Biochem., 63 (5), pp.934-936 (1999)
66 K. Ishihara, N. Nakajima, T. Itoh, H. Yamaguchi, K. Nakamura, T. Furuya and H. Hamada;
A chemoenzymatic synthesis of aromatic carboxylic acid vinyl esters,
Journal of Molecular Catalysis B : Enzymatic, 7, pp.307-310 (1999)
67 N. Nakajima, M. Sugimoto, K. Ishihara, K. Nakamura and H. Hamada;
Further characterization of earthworm serine proteases : Cleavage specificity
against peptide substrates and on
autolysis,
Biosci. Biotechnol. Biochem., 63 (11), pp.2031-2033 (1999)