2000年〜2009年 執筆論文


00年
68 T. Okuzumi, Y. Kaji, H. Hamada and Y. Fujimoto;
  Mechanism of the second methylation in sitosterol side-chain biosynthesis in higher plants:
  Metabolic fate of 28-hydrogens of 24-methylenecholesterol in Morus alba cell cultures,
  Tetrahedron Letters,41, pp.3623-3626 (2000)

69 K. Sanada, A. Kawaguchi, T. Furuya and H. Hamada;
  Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha,
  Plant Biotechnology,
17 (4), pp.12 (2000)

70 K. Sanada, A. Kawabe, T. Furuya, K. Ishihara, N. Nakajima and H. Hamada;
  High production of β-thujaplicin with Thuja dolabrata var. hondai cells in a semi-continuous culture system,
  Journal of Molecular Catalysis B: Enzymatic,11, pp.59-61 (2000)

71 K. Nakamura, R. Yamanaka, K. Tohi and H. Hamada;
  Cyanobacterium-catalyzed asymmetric reduction of ketones,
  Tetrahydron Letters,41, pp.6799-6802 (2000)

72 K. Ishihara, H. Yamaguchi, H. Hamada, K. Nakamura and N. Nakajima;
  Asylmmetric reduction of α-keto esters with thermophilic actinomycete:
  Purification and characterization of α-keto ester reductase from Streptomyces thermocyaneoviolaceus IFO 14271,
  Journal of Molecular Catalysis B: Enzymatic, 10, pp.419-428 (2000)

73 K. Ishihara, H. Yamaguchi, N. Adachi, H. Hamada and N. Nakajima;
  Stereocontrolled reduction of α- and β-keto esters with micro green algae, Chlorella strains,
  Biosci. Biotechnol. Biochem.,64 (10), pp.2099-2103 (2000)

74 K. Ishihara, H. Yamaguchi, H. Hamada, N. Nakajima and K. Nakamura;
  Stereocontrolled reduction of α-keto esters with thermophilic sntinomycete,
  Streptomyces thermocyaneoviolaceus IFO 14271, Journal of Molecular Catalysis B : Enzymatic,10, pp.429-434 (2000)

75 N. Nakajima, K. Ishihara, H. Hamada, S. Kawabe and T. Furuya;
  Regioselective acylation of flavonoid glucoside with aromatic acid by an enzymatic reaction system from cultured   

  cells of Ipomoea batatas,
  Journal of Bioscience and Bioengineering, 90 (3), pp.347-349 (2000)

01年
76 W. Chai, H. Hamada, J. Suhara and C. A. Horiuchi;
  Biotransformation of (+)-(-)-camphorquinones by plant cultured cells,
  Phytochemistry,57, pp.669-673 (2001)

77 H. Hamada, T. Tanaka, T. Furuya, H. Takahata and H. Nemoto;
  Hydroxylation of benzylic and allylic sites by plant cultured suspension cells,
  Tetrahedron Letters, 42, pp.909-911 (2001)

78 K. Ishihara, N. Nakajima, H. Yamaguchi, H. Hamada and Y. Uchimura;
  Stereoselective reduction of keto esters with marine micro algae,
  Journal of Molecular Catalysis B: Enzymatic, 15, pp.101-104 (2001)

79 N. Nakajima, K. Ishihara and H. Hamada;
  Functional glucosylation of kojic acid and daidzein with the Eucalyptus membrane-associated

  UDP-glucosyltransferase reaction system,
  Journal of Bioscience and Bioengineering, 92 (5), pp.469-471 (2001)

80 H. Hamada, K. Nishida, T. Furuya, K. Ishihara and N. Nakajima;
  Preparation of a new pepper: chemoenzymatic synthesis of capsaicin oligosaccharide and 8-nordihydrocapsaicin   

  oligosaccharide,
  Journal of Molecular Catalysis B: Enzymatic, 16, pp.115-119 (2001)

81 Z. Siding, H. Hamada, K. Sanada and A. T. Tu;
  Raman and IR spectroscopic study of taxol and its analogue, 10-deacetylbaccatinV,
  Asian Journal of Spectroscopy,1, pp.11-16 (2001)

82 H. Hamada, T. Miura, H. Kumobayashi, T. Matsuda, T. Harada and K. Nakamura;
  Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum,
  Biotechnology Letters, 23, pp.1603-1606 (2001)

02年

83 H. Hamada, Y. Miyamoto, T. Furuya, N. Nakajima, K. Ishihara and H. Hamada;
  Bioreduction of alkyl phenyl ketones and cyclopentanone derivatives by plant cultured suspension cells,
  Plant Biotechnology, 19 (3), pp.203-205 (2002)

84 H. Hamada, R. Tomi, Y. Asada and T. Furuya;
  Phytoremediation of bisphenol A by cultured suspension cells of Eucalyptus perriniana regioselective hydroxylation

  and glycosylation,
  Tetrahedron Letters, 43, pp.4087-4089 (2002)

85 K. Ishihara, Y. Nishimura, T. Kubo, C. Okada, H. Hamada and N. Nakajima;
  Enzyme-catalyzed Acylation of Plant Polyphenols for Interpretation of Their Functions,
  Plant Biotechnology, 19 (3), pp. 211-214 (2002)

86 Y. Matsuura, W. Chai, E. Endoh, J. Suhara, H. Hamada, C. A. Horiuchi;
  Oxidative cleavage of the C-C bond of 3,6-dialkylcyclohexane-1,2-diones by cells suspension cultures of  

  Marchantia  polymorpha,
  Phytochemistry,
61, pp.669-673 (2002)

03年
87 K. Ishihara, H. Hamada, T. Hirata, N. Nakajima;
  Biotransformation using plant cultured cells,
  Journal of Molecular Catalysis B : Enzymatic, 23, pp.145-170 (2003)

88 H. Hamada, S. Ohiwa, T. Nshida, H. Katsuragi, T. Takeda, H. Hamada, N. Nakajima and K. Ishihara;
  One-step Glucosylation of Capsaicinoids by Cultured Cells of Phytolacca Americana,
  Plant Biotechnology, 20 (3), pp.253-255 (2003)

89 H. Hamada, Y. Kondo, K. Ishihara, N. Nakajima, H. Hamada, R. Kurihara and T. Hirata;
  Stereoselective Biotransformation of Limonene and Limonene Oxide by Cyanobacterium, Synechococcus sp. PCC

  7942,
  Journal of Bioscience and Bioengineering,96 (6), pp.581-584 (2003)

90 谷由美子, 藤岡敏明, 浜田博喜, 国松己歳, 古市幸生;
  “バニリルノナンアミド-β-D-グルコシドによる高脂血症ラットの血清脂質低下作用”,
  日本栄養・食糧学会誌, 56 (3), pp.181-187 (2003)

91 Y. Matsuya, T. Kawaguchi, H. Nemoto, H. Nozaki and H.Hamada;
  A new efficient synthesis of both enantiomers of macrosphelide core: A poecursor for functionalized mcrosphelides,
  Heterocycles, 59 (2), pp.481-484 (2003)

04年
92 Hamada, H., Ishihara, K., Nakajima, N., Hamada, H., Williams, H.,J., Scott, A., I.,
  Enzymatic Oxidation of 1,4- and 1,8-Cineole using Plant Cultured Cells of Catharanthus Roseus,
  Letters in Organic Chemistry,1, pp.171-172 (2004)

93 T. Hirata, A. Takarada, A. Matsushima, Y. Kondo and H. Hamada;
  Asymmetric hydrogenation of N-substituted maleimides by cultured plant cells,
  Tetrahedron, 15, pp.15-16 (2004)

94 K. Shimoda, N. Kubota, H. Hamada, M. Kaji, and T. Hirata;
  Asymmetric reduction of enones with Synechococcus sp. PCC 7942,
  Tetrahedron, 15, pp.1677-1679 (2004)

95 S. Otani, Y. Kondo, Y. Asada, T. Fureya, H. Hamada, N. Nakajima, K. Ishihara, H. Hamada;
  Biotransformation of (+)-catechin by cultured suspension cells of Eucalyptus perriniana,
  Plant Biotechnology,
21 (5), pp.407-409 (2004)

96 H. Nomoto, M. Iigo, H. Hamada, S. Kojima, H. Tsuda;
  Chemoprevention of Colorectal Cancer by Grape Seed Proanthocyanidin is Accompanied by a Decrease
  in Proliferation and Increase in Apoptosis,
  Nutrition and Cancer,49(1), pp.81-88 (2004)

97 K. Shimoda, N. Kubota, H. Hamada, S. Yamane, and T. Hirata;
  Asymmetric Transformation of Enones with Synechococcus sp. PCC 7942,
  The Chemical Society of Japan, 77 (12),
  pp.2269-2272 (2004)

98 Y. Tani, T. Fujioka, M. Sumioka, Y. Furuichi, H. Hamada, and T. Watanabe;
  Effects of Capsinoid on Serum and Liver Lipids in Hyperlipidemic Rats,
  J. Nutr. Sci. Vitaminol,50, pp.351-355 (2004)

99 K. Shimoda, N. Kubota, H. Hamada;
  Asymmetric reduction of α,β-unsaturated carbonyl compounds with reductases from Nicotiana tabacum,
  Tetrahedron
, 15, pp.2443-2446 (2004)

100 K. Shimoda, N. Kubota, H. Hamada;
   Enantioselective glucosylation of (±)-secondary alcohols with plant glucosyltransferases,
   Tetrahedron, 15, pp.2319-2321 (2004)

05年
101 T. Hirata, A. Takarada, ME F. Hegazy, Y. Sato, A. Matsushima, Y. Kondo, A. Matsuki, H. Hamada,
   Hydrogenation of the C-C double bond of maleimides with cultured plant cells,
   Journal of Molecular Catalysis B : Enzymatic, 32 (4), pp.131-134 (2005)

06年
102 K. Shimoda, N. Kubota, H. Hamada, H. Hamada;
   Diastereoselective reduction of β-keto carbonyl compounds by cultured plant cells,
   Tetrahedron Letter, 47 (10), pp.1541-1544 (2006)

103 Y. Kondo, K. Shimoda, N. Kubota, H. Hamada, H. Hamada,
   Biotransformation of monofluorophenols by plant cultured cells of Eucalyptus perriniana,
   Plant Biotechnology,
23, pp.329-331 (2006)

104 Y. Kondo, K. Shimoda, J. Takimura, H. Hamada, H. Hamada,
   Enzymatic glycosylation of vitamin E homologues by cultured plant cells,
   Chem.Lett,
35 (3), pp.324-325 (2006)

105 Y. Kondo, K. Shimoda, K. Miyahara, H. Hamada, H. Hamada,
   Regioselective hydroxyration, reduction, and glycosylation of diphenyl compounds by cultured plant cells of Eucalyptus

   perriniana,
   Plant Biotechnology,
23, pp.291-296 (2006)

106 K. Shimoda, Y. Kondo, K. Abe, H. Hamada, H. Hamada,
   Formation of water-soluble vitamin derivatives from lipophilic vitamins by cultured plantcells,
   Tetrahedron Letters, 47,p.2695 (2006)

107 K. Shimoda, Yoko Kondo, Tomohisa Nishida, Hatsuyuki Hamada, Nobuyoshi Nakajima, Hiroki Hamada,
   Biotransformation of thymol, carvacrol, and eugenol by cultured cells of Eucalyptus perriniana
   Phytochemistry, 67, pp.2256-2261 (2006)

108 Hiroki Hamada, Kohji Ishihara, Noriyoshi Masuoka, Katsuhiko Mikuni, and Nobuyoshi Nakajima,
   Enhancement of Water-Solubility and Bioactivity of Paclitaxel Using Modified Cyclodextrins
   Journal of Biosscience and Bioengineering, 102(4), pp.369-371 (2006)

07年
109 Kei Shimoda, Toshio Harada, Hatsuyuki Hamada, Nobuyoshi Nakajima, Hiroki Hamada,
   Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana
   Phytochemistry, 68, pp.487-492 (2007)

110 Kei Shimoda, Naoji Kubota, Toshifumi Hirata, Yoko Kondo Hiroki Hamada
   Stereoselective reduction of 2-butenolides to chiral butanolides by reductases from cultured cells of Glycine max
   Tetrahedron Letters, pp.1345-1347 (2007)

111 Kei Shimoda, Naoji Kubota, Nobuyoshi Nakajima, Hatsuyuki Hamada, Hiroki Hamada
   High Production of (2S,3S)-3-hydroxy-2-methylbutanoate by immobilized plant cells of Marchantia Polymorpha
   Acta Biologica Hungarica, 58(1), pp.219-223 (2007)

112 Kei Shimoda, Yoko Kondo, Masaaki Akagi, Koichi Abe, Hatsuyuki Hamada, Hiroki Hamada
   Synthesis of α-Tocopheryl Disaccharides as Potential Antiallergic Agents
   Chemistry Letters, 36, pp.570-571 (2007)

113 Kei Shimoda, Soonil Kwon, Akiko Utsuki, Shingo Ohiwa, Hisashi Katsuragi, Naoko Yonemoto, Hatsuyuki Hamada,

   Hiroki,  Hamada
   Glycosylation of capsaicin and 8-nordihydorocapsaicin by cultured cells of Catharanthus roseus
   Phytochemistry ,68, pp.1391-1396 (2007)

114 Kei Shimoda, Yoko Kondo, Masaaki Akagi, Koichi Abe, Hatsuyuki Hamada, Hiroko Hamada
   Glycosylation of tocopherols by cutured cells of Eucalyptus perriniana
   Phytochemistry , 68, pp.2678-2683(2007)

115 Kei Shimoda, Takafumi Hara, Hatsuyuki Hamada, Hiroki Hamada
   Synthesis of curcumin β-maltooligosides through biological glycosylation with Strophanthus gratuscell culture and

   cyclodextrin glucanotransferase
   Tetrahedron Letters , 48, pp.4029-4032(2007)

116 Willy J. Peumans, Elke Fouquaert, Alain Jauneau, Pierre Rouge, Nausicaa Lannoo, Hiroki Hamada, Richard Alvarez,  

   Bart Devreese, Els J.M. Van Damme
   The liverwort Marchantia polmorpha expresses orthologs of the fungal Agaricus bisporus agglutinin family
   Plant Physiology, 144, pp.637-647 (2007)

117 Kei Shimoda, Nobuyushi Nakajima, Hatsuyuki Hamada, Kohji Ishihara and Hiroki Hamada
   Glucosylation of phenols and phenylalkyl alcohols using plant cultured cells
   Biotechnology journal, 2, pp.1294-1296 (2007)

118 Kei Shimoda, Takanao Otsuka, Yoko Morimoto, Hatsuyuki Hamada, Hiroki Hamada
   Glycosylation and Malonylation of Quercetim, Epicatechin, and Catechin by Cultured Plant Cells
   Chemistry Letters, 36, pp.1292-1293 (2007)

08年

120 Kei Shimoda, Hatsuyuki Hamada, Hiroki Hamada
   Glycosylation of hesperetin by plant cell cultures
   Phytochemistry, 69, pp.1135-1140 (2008)

121 Kei shimoda, Katsuhiko Mikuni, Kiyoshi Nakajima, Hatsuyuki Hamada, and Hiroki Hamada
   Biological Degradation of Taxol by Action of Cultured Cells on 7-Acetyltaxol-2"-yl Glucoside
   Chemistry Letters, 37, pp.362-363 (2008)

122 Kei Shimoda, Sou Sakamoto, Nobuyoshi Nakajima, Hatsuyuki Hamada, and Hiroki Hamada
   Synthesis of Unnatural Mono- and Oligosaccharides of Farnesol,Geraniol,and(S)-Perillyl Alcohol by Biocatalytic

   Glycosylations
   Chemistry Letters, 37,pp.556-557 (2008)

123 Soonil Kwon, Kei Shimoda, Hatsuyuki Hamada, Kohji Ishihara, Noriyoshi Masuoka, Hiroki Hamada
   High production of β-thujaplicin glycosides by immobilized plant cells of Nicotiana tabacum
   Acta Biologica Hungarica, 59,pp.347-355 (2008)

124 Kei Shimoda, Noriaki Sato, Tatsunari Kobayashi, Hatsunari Hamada, Hiroki Hamada
   Glycosylation of daidzein by the Eucalyptus cell cultures
   Phytochemistry, 69,pp.2303-2306 (2008)

125 Kei Shimoda, Tatsunari Kobayashi,Masaaki Agagi, Hatsuyuki Hamada, Hiroki Hamada
   Synthesis of Oligosaccharides of Genisutein and Quercetin as Potential Anti-inflammatory Agents
   Chemistry Letters, 37,pp.876-877 (2008)

126 Tomoo Honda, Keiji Hirai, Sonnil Kwon, Hisashi Katsuragi, Hiroki Hamada and Yoshifumi Katayama
   Action of Capsaicin Glucosides on Intestinal Transport in Rats

   Electrochemistry, 76,pp.583-585 (2008)

127 Kohji Ishihara, Chiaki Kato, Hitomi Yamaguchi, Rieko Iwai, Momoko Yoshida, Natsumi Ikeda, Hiroki Hamada,

   Noriyoshi Masuoka, and Nobuyoshi Nakajima
   Streoselective Reduction of Carbonyl Compounds with Actinomycete:Purification and Characterization of

   Three α-Keto Ester Reductases from Streptomyces avermitilis Bioscience,
   Biotechnology and Biochemistry
, 72,pp.3249-3257 (2008)

128 Kei Shimoda, Eriko Kimura, Hatsuyuki Hamada, Hiroki Hamada
   Production of curcumin Oligosaccharidesd by Glycosylation with Parthenocissus tricuspidata
   Japanese Journal of Plant Science, 2,pp.43-45 (2008)

129 Masahiko Nagaki, Hiroto Imaruoka, Jun Nawakami, Norimasa Ohya, Hiroki Hamada, Hiroshi Sagami, Tanetoshi Koyama
   Bio-catalytic Synthesis of Isoprenoids by Cultured Cells of Cucurbita maxima
   Transactions of the Materials Research Society of Japan, 33, pp.819-822  (2008)

09年
130 Yoshimi Niwano, Fumiaki Beppu, Taichi Shimada, Rika Kyan, Kazumasa Yasura, Minori Tamaki, Michinori Nishino,   

   Yoshiyuki Midorikawa, Hiroki Hamada
   Extensive Screening for Plant Foodstuffs in Okinawa, Japan with Anti-Obese Activity on Adipocytes In Vitro
   Plant Foods for Human Nutrition, 64, pp.6-10 (2009)

131 Kei Shimoda, Hiromasa Ishimoto, Tomoyuki Kamiue, Tatsunari Kobayashi, Hatsuyuki Hamada, Hiroki Hamada
   Glycosylation of sesamol by cultured plant cells
   Phytochemistry,70, pp.207-210 (2009)

132 Kei Shimoda, Naoji Kubota, Hatsuyuki Hamada, Tatsunari Kobayashi, Hiroki Hamada, Siddiqi M. Shafi and Nobuyoshi Nakajima
   Production of (2R,3S)-2-benzamidomethyl-3-hydroxybutanoates by Immobilized Plant Cells of Parthenocissus

   Tricuspidata
   Biochemistry Insights, 2, pp.1-3 (2009)

133 Akino Noguchi, Satoshi Kunikane, Hiroki Homma, Wenhai Liu, Takashi Sekiya, Miho Hosoya, Soonil Kwon, Shingo  

   Ohiwa, Hisashi Katsuragi, Tokuzo Nishino, Seiji Takahashi, Hiroki Hamada, Toru Nakayama
   Identification of an inducible glucosyltransferase from Phytolacca americana L.cells that are capable of

   glucosylating capsaicin
   Plant Biotechnology, 26, pp.285-292 (2009)

134 Kei Shimoda, Naoji Kubota, Yoko Kondo, Daisuke Sato and Hiroki Hamada
   Glycosylation of Fluorophenols by Plant Cell Cultures
   Intermational Journal of Molcular Sciences, 10, pp.1942-1949 (2009)

135 K.Shimoda and H.Hamada
   Bioremediation of Bisphenol A and Benzophenone by Glycosylation with Immobilized Marine Microalga Pavlova sp.
   Environmental Health Insights, 3, pp.89-94 (2009)

136 Kei Shimoda, Hatsuyuki Hamada and Hiroki Hamada
   Phytoremediation of Benzophenone and Bisphenol A by Glycosylation with Immobilized Plant Cells
   Biochemistry Insights, 3, pp.19-25 (2009)

137 Fumiaki Beppu, Yoshimi Niwano, Rika Kyan, Kazumasa Yasura, Minori Tamaki, Michinori Nishino, Yoshiyuki Midorikawa,

   Hiroki Hamada 
   Hypolipidemic effects of ethanol extracts of Citrus depressa and Annona atemoya, typical plant foodstuffs in

   Okinawa, Japan on KKAy mice fed with moderately high fat diet
   Food Science and Technology Research, 15,(2009)

138 Kei Shimoda, Daisuke Sato, Hiroki Hamada
   Synthesis of β-Maltooligosaccharides of α-Tocopherol Derivatives by Xanthomonas campestris Cyclodextrin    

   Glucanotransferase and Their Anti-allergic Activity
   Chemistry Letters, 38, pp.930-931 (2009)

139 Kei Shimoda, Masaaki Akagi and Hiroki Hamada
   Production of β-Maltooligosaccharides of a- and δ-Tocopherols by Klebsiella Pneumoniae and Cyclodextrin   

   Glucanotransferase as Anti-Allergic Agents
   Molecules,14,pp.3106-3144 (2009) 



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